Polysaccharides from Agaricus bisporus and Agaricus brasiliensis show similarities in their structures and their immunomodulatory effects on human monocytic THP-1 cells. Smiderle FR, Ruthes AC, van Arkel J, Chanput W, Iacomini M, Wichers HJ, Van Griensven LJ. BMC Complement Altern Med. 2011 Jul 25;11:58. doi: 10.1186/1472-6882-11-58. PMID: 21787425

Diabetes Mellitus - Type 1

The Effect of Agaricus brasiliensis and Ganoderma lucidum Medicinal Mushroom Administration on the L-arginine/Nitric Oxide System and Rat Leukocyte Apoptosis in Experimental Type 1 Diabetes Mellitus. Yurkiv B, Wasser SP, Nevo E, Sybirna NO. Int J Med Mushrooms. 2015;17(4):339-50. PMID: 25954960

A stable culturing method and pharmacological effects of the Agaricus blazei. Higaki M, Eguchi F, Watanabe Y. Nihon Yakurigaku Zasshi. 1997 Oct;110 Suppl 1:98P-103P. Japanese. PMID: 9503414

Effect of medicinal mushrooms on blood cells under conditions of diabetes mellitus. Vitak T, Yurkiv B, Wasser S, Nevo E, Sybirna N. World J Diabetes. 2017 May 15;8(5):187-201. doi: 10.4239/wjd.v8.i5.187. Review.

Rheumatoid Arthritis

Antioxidant Action of an Aqueous Extract of Royal Sun Medicinal Mushroom, Agaricus brasiliensis (Agaricomycetes), in Rats with Adjuvant-Induced Arthritis. de Souza ACDS, Gonсalves GA, Soares AA, de Sá-Nakanishi AB, de Santi-Rampazzo AP, Natali MRM, Peralta RM, Bracht A. Int J Med Mushrooms. 2018;20(2):101-117. doi: 10.1615/ IntJMedMushrooms.2018025309. PMID: 29773003