Gastro Intestinal

Colon

The Agaricus blazei-Based Mushroom Extract, Andosan™, Protects against Intestinal Tumorigenesis in the A/J Min/+ Mouse. Hetland G, Eide DM, Tangen JM, Haugen MH, Mirlashari MR, Paulsen JE. PLoS One. 2016 Dec 21;11(12):e0167754. doi: 10.1371/journal.pone.0167754. eCollection 2016.

Effect of Agaricus blazei Murrill extract on HT-29 human colon cancer cells in SCID mice in vivo. Wu MF, Chen YL, Lee MH, Shih YL, Hsu YM, Tang MC, Lu HF, Tang NY, Yang ST, Chueh FS, Chung JG. In Vivo. 2011 Jul-Aug;25(4):673-7. PMID: 21709013

Stomach

Blazein of a new steroid isolated from Agaricus blazei Murrill (himematsutake) induces cell death and morphological change indicative of apoptotic chromatin condensation in human lung cancer LU99 and stomach cancer KATO III cells. Itoh H, Ito H, Hibasami H. Oncol Rep. 2008 Dec;20(6):1359-61. PMID: 19020714

Induction of G2/M arrest and apoptosis in human gastric epithelial AGS cells by aqueous extract of Agaricus blazei. Jin CY, Choi YH, Moon DO, Park C, Park YM, Jeong SC, Heo MS, Lee TH, Lee JD, Kim GY. Oncol Rep. 2006 Dec;16(6):1349-55. PMID: 17089060