Lung

Possible reduction of hepatoma formation by Smmu 7721 cells in SCID mice and metastasis formation by B16F10 melanoma cells in C57BL/6 mice by Agaricus blazei murill extract. Wu MF, Lu HF, Hsu YM, Tang MC, Chen HC, Lee CS, Yang YY, Yeh MY, Chung HK, Huang YP, Wu CC, Chung JG. In Vivo. 2011 May-Jun;25(3):399-404. PMID: 21576414

A low molecular weight polysaccharide isolated from Agaricus blazei Murill (LMPAB) exhibits its anti-metastatic effect by down-regulating metalloproteinase-9 and up-regulating Nm23-H1. Niu YC, Liu JC, Zhao XM, Cao J. Am J Chin Med. 2009;37(5):909-21. PMID: 19885951

Blazein of a new steroid isolated from Agaricus blazei Murrill (himematsutake) induces cell death and morphological change indicative of apoptotic chromatin condensation in human lung cancer LU99 and stomach cancer KATO III cells. Itoh H, Ito H, Hibasami H. Oncol Rep. 2008 Dec;20(6):1359-61. PMID: 19020714

Suppressing effects of daily oral supplementation of beta-glucan extracted from Agaricus blazei Murill on spontaneous and peritoneal disseminated metastasis in mouse model. Kobayashi H, Yoshida R, Kanada Y, Fukuda Y, Yagyu T, Inagaki K, Kondo T, Kurita N, Suzuki M, Kanayama N, Terao T. J Cancer Res Clin Oncol. 2005 Aug;131(8):527-38. Epub 2005 May 10. PMID: 15883813

solation of an anti-angiogenic substance from Agaricus blazei Murill: its antitumor and antimetastatic actions. Kimura Y, Kido T, Takaku T, Sumiyoshi M, Baba K. Cancer Sci. 2004 Sep;95(9):758-64. PMID: 15471563

Isolation of an antitumor compound from Agaricus blazei Murill and its mechanism of action. Takaku T, Kimura Y, Okuda H. J Nutr. 2001 May;131(5):1409-13. PMID: 1340091