Sarcoma

Mycelial antineoplastic activity of Agaricus blazei. Bertéli MB, Umeo SH, Bertéli A, do Valle JS, Linde GA, Colauto NB. World J Microbiol Biotechnol. 2014 Aug;30(8):2307-13. doi: 10.1007/s11274-014-1656-6. Epub 2014 Apr 27. PMID: 24770840

A polysaccharide from Agaricus blazei inhibits proliferation and promotes apoptosis of osteosarcoma cells. Wu B, Cui J, Zhang C, Li Z. Int J Biol Macromol. 2012 May 1;50(4):1116-20. doi: 10.1016/j.ijbiomac.2012.02.023. Epub 2012 Feb 27. PMID: 22390851

Endotoxin contamination of Agaricus blazei Murrill extract enhances murine immunologic responses and inhibits the growth of sarcoma 180 implants in vivo. Kobayashi H, Masumoto J. J Environ Pathol Toxicol Oncol. 2010;29(2):159-68. PMID: 20932249

Effects of Agaricus brasiliensis mushroom in Walker-256 tumor-bearing rats. Jumes FM, Lugarini D, Pereira AL, de Oliveira A, Christoff Ade O, Linde GA, do Valle JS, Colauto NB, Acco A. Can J Physiol Pharmacol. 2010 Jan;88(1):21-7. doi: 10.1139/Y09-111. PMID: 20130735

Immunostimulatory activities of a low molecular weight antitumoral polysaccharide isolated from Agaricus blazei Murill (LMPAB) in Sarcoma 180 ascitic tumor-bearing mice. Niu YC, Liu JC, Zhao XM, Su FQ, Cui HX. Pharmazie. 2009 Jul;64(7):472-6. PMID: 19694186

A low molecular weight polysaccharide isolated from Agaricus blazei suppresses tumor growth and angiogenesis in vivo. Niu YC, Liu JC, Zhao XM, Wu XX. Oncol Rep. 2009 Jan;21(1):145-52. PMID: 19082455

In vivo growth-inhibition of Sarcoma 180 by an alpha-(1–>4)-glucan-beta-(1–>6)-glucan-protein complex polysaccharide obtained from Agaricus blazei Murill. Gonzaga ML, Bezerra DP, Alves AP, de Alencar NM, Mesquita Rde O, Lima MW, Soares Sde A, Pessoa C, de Moraes MO, Costa-Lotufo LV. J Nat Med. 2009 Jan;63(1):32-40. doi: 10.1007/s11418-008-0286-4. Epub 2008 Aug 23. PMID: 18726068

Amelioration of skewed Th1/Th2 balance in tumor-bearing and asthma-induced mice by oral administration of Agaricus blazei extracts. Takimoto H, Kato H, Kaneko M, Kumazawa Y. Immunopharmacol Immunotoxicol. 2008;30(4):747-60. doi: 10.1080/08923970802279092 . PMID: 18720167

Oral administration of Agaricus blazei (H1 strain) inhibited tumor growth in a sarcoma 180 inoculation model. Lee YL, Kim HJ, Lee MS, Kim JM, Han JS, Hong EK, Kwon MS, Lee MJ. Exp Anim. 2003 Oct;52(5):371-5. PMID: 14625400

Antitumor beta glucan from the cultured fruit body of Agaricus blazei. Ohno N, Furukawa M, Miura NN, Adachi Y, Motoi M, Yadomae T. Biol Pharm Bull. 2001 Jul;24(7):820-8. PMID: 11456124

Isolation of an antitumor compound from Agaricus blazei Murill and its mechanism of action.Takaku T, Kimura Y, Okuda H. J Nutr. 2001 May;131(5):1409-13. PMID: 11340091

Anti-tumor polysaccharide from the mycelium of liquid-cultured Agaricus blazei mill. Mizuno M, Minato K, Ito H, Kawade M, Terai H, Tsuchida H. Biochem Mol Biol Int. 1999 Apr;47(4):707-14. PMID: 10319424

Antitumor effect of a peptide-glucan preparation extracted from Agaricus blazei in a double-grafted tumor system in mice. Ebina T, Fujimiya Y. Biotherapy. 1998;11(4):259-65. PMID: 9950102

Polysaccharides from Agaricus blazei stimulate lymphocyte T-cell subsets in mice. Mizuno M, Morimoto M, Minato K, Tsuchida H. Biosci Biotechnol Biochem. 1998 Mar;62(3):434-7. PMID: 9571772

Antitumor effects of a new polysaccharide-protein complex (ATOM) prepared from Agaricus blazei (Iwade strain 101) “Himematsutake” and its mechanisms in tumor-bearing mice. Ito H, Shimura K, Itoh H, Kawade M. Anticancer Res. 1997 Jan-Feb;17(1A):277-84. PMID: 9066665

Inhibitory action of a (1–>6)-beta-D-glucan-protein complex (F III-2-b) isolated from Agaricus blazei Murill (“himematsutake”) on Meth A fibrosarcoma-bearing mice and its antitumor mechanism. Itoh H, Ito H, Amano H, Noda H. Jpn J Pharmacol. 1994 Oct;66(2):265-71. PMID: 7869611