Hypercholesterolmia (cholesterol)

Agaricus brasiliensis (sun mushroom) affects the expression of genes related to cholesterol homeostasis. de Miranda AM, Rossoni Júnior JV, Souza E Silva L, Dos Santos RC, Silva ME, Pedrosa ML. Eur J Nutr. 2016 May 5. [Epub ahead of print] PMID: 27151383

Aqueous Extract of Agaricus blazei Murrill Prevents Age-Related Changes in the Myenteric Plexus of the Jejunum in Rats. de Santi-Rampazzo AP, Schoffen JP, Cirilo CP, Zapater MC, Vicentini FA, Soares AA, Peralta RM, Bracht A, Buttow NC, Natali MR. Evid Based Complement Alternat Med. 2015;2015:287153. doi: 10.1155/2015/287153. Epub 2015 Apr 16. PMID: 25960748

Hypolipidemic effect of the edible mushroom Agaricus blazei in rats subjected to a hypercholesterolemic diet. de Miranda AM, Ribeiro GM, Cunha AC, Silva LS, dos Santos RC, Pedrosa ML, Silva ME. J Physiol Biochem. 2014 Mar;70(1):215-24. doi: 10.1007/s13105-013-0295-y. Epub 2013 Nov 8. PMID: 24203633

Hypertension (Blood Pressure)

Agaricus brasiliensis KA21 improves circulatory functions in spontaneously hypertensive rats. Tsubone H, Makimura Y, Hanafusa M, Yamamoto Y, Tsuru Y, Motoi M, Amano S. J Med Food. 2014 Mar;17(3):295-301. doi: 10.1089/jmf.2013.2934. Epub 2014 Jan 16. PMID: 24433071

[A stable culturing method and pharmacological effects of the Agaricus blazei]. Higaki M, Eguchi F, Watanabe Y. Nihon Yakurigaku Zasshi. 1997 Oct;110 Suppl 1:98P-103P. Japanese. PMID: 19503414