Immunomodulatory effects of the Agaricus blazei Murrill-based mushroom extract AndoSan in patients with multiple myeloma undergoing high dose chemotherapy and autologous stem cell transplantation: a randomized, double blinded clinical study. Tangen JM, Tierens A, Caers J, Binsfeld M, Olstad OK, Trøseid AM, Wang J, Tjønnfjord GE, Hetland G. Biomed Res Int. 2015;2015:718539. doi: 10.1155/2015/718539. Epub 2015 Jan 18. PMID: 25664323

 Agaricus blazei Murill enhances doxorubicin-induced apoptosis in human hepatocellular carcinoma cells by NFκB-mediated increase of intracellular doxorubicin accumulation. Lee JS, Hong EK. Int J Oncol. 2011 Feb;38(2):401-8. doi: 10.3892/ijo.2010.852. Epub 2010 Dec 3. PMID: 21132265

Beta-glucan extracted from the medicinal mushroom Agaricus blazei prevents the genotoxic effects of benzo[a]pyrene in the human hepatoma cell line HepG2. Angeli JP, Ribeiro LR, Bellini MF, Mantovani MS. Arch Toxicol. 2009 Jan;83(1):81-6. doi: 10.1007/s00204-008-0319-5. Epub 2008 Jun 5. PMID: 18528685

Protective effects of beta-glucan extracted from Agaricus brasiliensis against chemically induced DNA damage in human lymphocytes. Angeli JP, Ribeiro LR, Gonzaga ML, Soares Sde A, Ricardo MP, Tsuboy MS, Stidl R, Knasmueller S, Linhares RE, Mantovani MS. Cell Biol Toxicol. 2006 Jul;22(4):285-91. Epub 2006 Jun 26. PMID: 16802105

Natural killer cell activity and quality of life were improved by consumption of a mushroom extract, Agaricus blazei Murill Kyowa, in gynecological cancer patients undergoing chemotherapy.  Ahn WS, Kim DJ, Chae GT, Lee JM, Bae SM, Sin JI, Kim YW, Namkoong SE, Lee IP. Int J Gynecol Cancer. 2004 Jul-Aug;14(4):589-94. PMID: 15304151 

Medicinal Properties and Clinical Effects of Culinary-Medicinal Mushroom Agaricus blazei Murrill (Agaricomycetideae) (Review) Takashi Mizuno  Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University, 4-13-9 Seinan-Cho, Fujieda-Shi 426-0063, Japan DOI: 10.1615/IntJMedMushr.v4.i4.30

VII International Symposium on Mushrooms in Brazil

The impact of Agaricus supplementation on the Natural Killer cell number as a potential adjuvant for cancer patients in chemotherapic treatment. Marcelo de Souza Gennari, Jorge Laerte Gennari, Janaina B Barletta Faculdades Integradas da Uniao Educational do Planalto Central, Cancer research Department MCM Sao Paulo – 
VII International Symposium on Mushrooms in Brazil