Immunomodulation

Immunomodulatory properties of medicinal mushrooms: differential effects of water and ethanol extracts on NK cell-mediated cytotoxicity. Lu CC, Hsu YJ, Chang CJ, Lin CS, Martel J, Ojcius DM, Ko YF, Lai HC, Young JD. Innate Immun. 2016 Oct;22(7):522-33. doi: 10.1177/1753425916661402. Epub 2016 Jul 28. PMID: 27469258

Extract of medicinal mushroom Agaricus blazei Murill enhances the non-specific and adaptive immune activities in BALB/c mice. Ni WY, Wu MF, Liao NC, Yeh MY, Lu HF, Hsueh SC, Liu JY, Huang YP, Chang CH, Chung JG. In Vivo. 2013 Nov-Dec;27(6):779-86. PMID: 24292582

Polysaccharides from Agaricus bisporus and Agaricus brasiliensis show similarities in their structures and their immunomodulatory effects on human monocytic THP-1 cells. Smiderle FR, Ruthes AC, van Arkel J, Chanput W, Iacomini M, Wichers HJ, Van Griensven LJ. BMC Complement Altern Med. 2011 Jul 25;11:58. doi: 10.1186/1472-6882-11-58. PMID: 21787425

Does the Agaricus blazei Murill mushroom have properties that affect the immune system? An integrative review. Lima CU, Cordova CO, Nóbrega Ode T, Funghetto SS, Karnikowski MG. J Med Food. 2011 Jan-Feb;14(1-2):2-8. doi: 10.1089/jmf.2010.0017. Epub 2010 Dec 4. Review. PMID: 21128829

Evaluation of Agaricus blazei in vivo for antigenotoxic, anticarcinogenic, phagocytic and immunomodulatory activities. Ishii PL, Prado CK, Mauro Mde O, Carreira CM, Mantovani MS, Ribeiro LR, Dichi JB, Oliveira RJ. Regul Toxicol Pharmacol. 2011 Apr;59(3):412-22. doi: 10.1016/j.yrtph.2011.01.004. Epub 2011 Feb 3. PMID: 21295629

Effect of an extract based on the medicinal mushroom Agaricus blazei Murill on expression of cytokines and calprotectin in patients with ulcerative colitis and Crohn’s disease. Førland DT, Johnson E, Saetre L, Lyberg T, Lygren I, Hetland G. Scand J Immunol. 2011 Jan;73(1):66-75. doi: 10.1111/j.1365-3083.2010.02477.x. PMID: 21129005

Effects of the medicinal mushroom Agaricus blazei Murill on immunity, infection and cancer. Hetland G, Johnson E, Lyberg T, Bernardshaw S, Tryggestad AM, Grinde B. Scand J Immunol. 2008 Oct;68(4):363-70. doi: 10.1111/j.1365-3083.2008.02156.x. Review. PMID: 18782264

Immunomodulatory effects of Agaricus blazei Murill in Balb/cByJ mice. Chan Y, Chang T, Chan CH, Yeh YC, Chen CW, Shieh B, Li C. J Microbiol Immunol Infect. 2007 Jun;40(3):201-8. PMID: 17639159

Antithetical effects of hemicellulase-treated Agaricus blazei on the maturation of murine bone-marrow-derived dendritic cells. Kawamura M, Kasai H, He L, Deng X, Yamashita A, Terunuma H, Horiuchi I, Tanabe F, Ito M. Immunology. 2005 Mar;114(3):397-409. PMID: 15720441

Isolation of an anti-angiogenic substance from Agaricus blazei Murill: its antitumor and antimetastatic actions. Kimura Y, Kido T, Takaku T, Sumiyoshi M, Baba K. Cancer Sci. 2004 Sep;95(9):758-64. PMID: 15471563