Support for Microbial Balance

Agaricus brasiliensis Mushroom Protects Against Sepsis by Alleviating Oxidative and Inflammatory Response.
Navegantes-Lima KC, Monteiro VVS, de França Gaspar SL, de Brito Oliveira AL, de Oliveira JP, Reis JF, de Souza Gomes R, Rodrigues CA, Stutz H, Sovrani V, Peres A, Romão PRT, Monteiro MC. Front Immunol. 2020 Jul 1;11:1238. doi: 10.3389/fimmu.2020.01238. eCollection 2020. PMID: 32714320

Medicinal Properties and Clinical Effects of Culinary-Medicinal Mushroom Agaricus blazei Murrill (Agaricomycetideae) (Review) Takashi Mizuno Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University, 4-13-9 Seinan-Cho, Fujieda-Shi 426-0063, Japan DOI: 10.1615/IntJMedMushr.v4.i4.30 

Support for Systemic Immune Response & Oxidative Balance

Agaricus brasiliensis Mushroom Protects Against Sepsis by Alleviating Oxidative and Inflammatory Response. Navegantes-Lima KC, Monteiro VVS, de França Gaspar SL, de Brito Oliveira AL, de Oliveira JP, Reis JF, de Souza Gomes R, Rodrigues CA, Stutz H, Sovrani V, Peres A, Romão PRT, Monteiro MC. Front Immunol. 2020 Jul 1;11:1238. doi: 10.3389/fimmu.2020.01238. eCollection 2020. PMID: 32714320

An extract of the mushroom Agaricus blazei Murill protects against lethal septicemia in a mouse model of fecal peritonitis. Bernardshaw S, Hetland G, Grinde B, Johnson E. Shock. 2006 Apr;25(4):420-5. PMID: 16670646

Modulating Microbial Signaling Pathways and Host Defense

Agaricus blazei hot water extract shows anti quorum sensing activity in the nosocomial human pathogen Pseudomonas aeruginosa.
Soković M, Ćirić A, Glamočlija J, Nikolić M, van Griensven LJ. Molecules. 2014 Apr 3;19(4):4189-99.doi:10.3390/molecules19044189. PMID: 24705563

Research on Nutritional Support for Host Immune Resilience

An extract of the mushroom Agaricus blazei Murill administered orally protects against systemic Streptococcus pneumoniae infection in mice. Bernardshaw S, Johnson E, Hetland G. Scand J Immunol. 2005 Oct;62(4):393-8. PMID: 16253127

Evaluating Immune Supporting Properties in Prokaryotic and Eukaryotic Systems